I've written before about the one major limitation of Herceptin - that it doesn't cross the brain-blood barrier. A couple of years ago (after meeting several young women with metastasis that had spread to the brain), I underwent a brain MRI. To my very great relief, there was no evidence of trouble but I think I'll will be requesting another before too long.
A few days ago, my friend Deanna posted a link to Breast Cancer? But Doctor...I Hate Pink and to Ann's take on the news that Viagra may help Herceptin to (ahem) penetrate the blood-brain barrier and thus help reduce the size of brain tumours.
"Herceptin, the wonder drug, has a flaw: it does not cross the blood-brain barrier. The blood-brain barrier wasIt's seriously interesting news but go read Ann's full post. It will make you laugh.
erecteddesigned by nature to protect our brains from dangerous substances, such as bad viagra jokes, but what it means for cancer patients is that certain drugs can't get through to kill swollenbad cells. Herceptin cannot treat HER2+ breast cancer that has engorged spreadinvaded the brain. Apparently, if you add a big largegenerous dose of Viagra to Herceptin, it adds enough thrustpower to break through that blood-brain barrier and bathe the brain in its heavinghealing properties."
Cross-posted to Mothers With Cancer.